Epiblepharon, not to be confused with the epicanthal fold, is an abnormal congential condition of the lower eyelid in which loose skin forms into a fold sitting high up and immediately in front of the lashes. Typically located along the inner half of the lower lid, it may extend all the way across in some cases. When the eye looks down but sometimes even when looking straight ahead, the lashes can bend inward and rub against the surface of cornea.

Found far more often in those of Asian descent, epiblepharon is most commonly noted during early childhood and may be outgrown as the anatomy of the lower lid becomes more mature. In cases where the condition is severe or the lashes are causing too much eye irritation, redness, light sensitivity, and tearing, surgery may be required to remove and/or tack down the skin forming the abnormal fold in a manner not unlike that used in some less-invasive versions of upper lid double eyelid surgery. The scar usually fades to nearly unnoticeable over several years.

While epiblepharon may be present in adults as well, most cases of in-turned lower lids and lashes in later life are more serious and secondary to eye disease or scarring. Known as "entropion," the entire lid and not just the top near the margin can become inverted.

Interestingly, epiblepharon in rarely seen in young children of European descent, who instead typically show a well-defined lower lid crease holding down the skin. Although these temporary creases later weaken and then disappear, epiblepharon does not follow.

The mechanism causing lower eyelid epiblepharon is closely related to the same anatomical variations seen in the upper lids of people with Asian "single" eyelids lacking a crease. Without natural tissue adhesion between the eyelid's closing (orbicularis) muscle and deeper support structures, the more mobile skin and muscle are free to float downward in the upper lid and upward in the lower lid.

When present in the adult lower eyelid but not associated with eye irritation, some people still elect to undergo surgical correction of epiblepharon for cosmetic reasons.